Chemical characterization, antioxidant activity, and cytotoxicity of fatty acids methyl esters from <i>Handroanthus impetiginosus</i> (Mart. ex DC.) Mattos (Bignoniaceae) seeds

Handroanthus impetiginosus, popularly known as “ipê-roxo”, is used in folk medicine to treat skin inflammations, infections, stomach diseases, and cancer. Fatty acid methyl esters (FAMEs) obtained from the esterification reaction of fatty acids (FA) found hexane extract (HE) seeds H. impetiginosus were identified by gas chromatography-mass spectrometry (GC-MS). The antioxidant cytotoxic activities HE FAMEs evaluated. Methyl palmitate, linoleate, oleate, stearate major HE. samples, especially HE, exhibited a significant potential analyzed ferric reducing ability power (FRAP) assay. In A. salina larvae bioassay, showed no effects, but high toxicity. This study reported, for first time, seeds.